Proteomics & Microarrays

=Proteomics=
 * Rationale: "Firstly, temporal and spatial expression of proteins is not apparent from gene expression analysis. Secondly, post-translational modifications (PTMs), static and dynamic, are rich in variety (more than 200 documented8) and typically not apparent from primary sequence data. Furthermore, even with the knowledge of a consensus sequence there are currently no general rules describing when and where phosphorylation, or other PTMs, takes place and how this functionally affects a biological system. Thirdly, and perhaps most importantly, inducible protein-ligand interactions cannot be measured by transcriptomics."
 * See Wikipedia entry for Proteomics.
 * What is Mass Spec From the Scripps Institute - this is a top notch institution and their primer covers many of the proteomics objectives in nitty-gritty detail. Well written, but very technical.
 * Mass Analyzers - Quadropole, MS/MS, TOF analysis, etc

=Microarrays= =References=
 * Microarray From University of Utah - excellent site for reinforcing concepts
 * Animated primer on Microarrays - more fun than lecture